User blog comment:Klaus13239/Does your god even lift?/@comment-8378042-20130506232125/@comment-25345260-20130507221318

Then they bear some sort of respect for Guthix, as if you listen to why they don't use runes, they say its because it is power that belongs to Gods, and slowly kills them to use it.

That, and when Jagex released a map of God's spheres of influence, Relleka and the Isles were Guthix Green. You can find this on the Runescape site wiki.

What better source, than the game makers?